Logan Liu | University of Illinois at Urbana-Champaign
Event Date:
November 10, 2016 – 3:30 PM
Location:
Burson 115
Event Date:
November 10, 2016 – 3:30 PM
Location:
Burson 115
Ph.D Nanoscale Science Seminar Series | Fall 2016
Logan Liu, PhD
University of Illinois at Urbana-Champaign
Department of Electrical and Computer Engineering and Department of Bioengineering
“Transforming Surface Plasmon Resonance into Mobile Biosensing Technology via Advanced Nanoplasmonic Devices”
Abstract:
Surface plasmon resonance (SPR) sensing is a powerful label free biomolecular detection technique used for drug screening, protein characterization, enzymatic kinetics studies and living cell membrane imaging. However special expensive optical spectroscopy equipment and systems are required for SPR sensing and imaging and they are not available in most research laboratories. In my talk, I will present our work on developing colorimetric and photonic resonator integrated nanoplasmonic resonance devices. Our colorimetric nano Lycurgus Cup Array (nanoLCA) sensor is the first colorimetric SPR sensor device (not based on colloidal nanoparticles) ever reported with a record high sensitivity so that the molecular and liquid SPR sensing can be visualized as transmitted or reflected color changes by color camera, photodiode or even naked eyes. With such a unique nanoplasmonic device, SPR biomolecular sensing and imaging is enabled on most ubiquitous instruments such as bright-field microscope, microplate reader and smartphones. I will show the label-free colorimetric and intensity-based nanoplasmonic sensing and imaging of DNA hybridization, cancer biomarker protein binding kinetics and drug metabolisms. I will also discuss about the nanoplasmon enhanced colorimetric bioassay applications.
Bio:
Prof. Logan Liu obtained his Ph.D. degree in bioengineering from University of California-Berkeley and UC-San Francisco. He finished his postdoctoral training in the Helen Diller comprehensive cancer center at San Francisco as well as Lawrence Livermore national lab where he was a Lawrence fellow. He is now an associate professor in Department of Electrical and Computer Engineering and Department of Bioengineering, University of Illinois at Urbana-Champaign. He has published over 100 journal and conference papers as well as several book chapters. His research focuses on designing and developing integrative bionanophotonic and mobile sensing technologies and devices for the applications of advanced nanomanufacturing, bioimaging, cancer diagnostics and therapy, environmental sensing and mobile health. Dr. Liu has been awarded for several major awards in the past including Lawrence fellowship, Presidential Early-Career Award for Scientists and Engineers (PECASE), lab-on-a-chip emerging investigator, Vodafone wireless innovation award and Nokia sensing XChallenge distinguished award. He is an elected fellow of American Institute for Medical and Biological Engineers. His research works on colorimetric nanoplasmonic device and mobile phone nanosensor were reported by Forbes, Wired magazine, Huffington Post, NBC, and many other major news media.