Juan Vivero-Escoto-Bacteria Destroyer

Dr. Vivero-Escoto’s lab has been quite busy and it really shows! Read below about 3 projects that have recently been funded:

Project Number1R16GM145434-01 Antimicrobial resistant bacteria (ARB) and genes (ARGs) are one of the biggest public health issues of the 21st century. In this project; we propose to develop a light-activated silver nanoparticulate system for the effective treatment of ARB and ARGs. The proposed research is relevant to public health because it will develop reliable technologies for the effective elimination of ARB and ARGs. Project Number1R15CA274239-01 Triple-negative breast cancer (TNBC) is associated with younger age, African American and Hispanic ethnicity background, BRCA gene-mutated populations, and has the worst prognosis compared with other types of breast cancer. In this project; we propose to develop RNA-loaded silica-based drug delivery nanocarrier to improve the photodynamic and siRNA therapy for the successful treatment of TNBC. Project Number1R01CA263897-01A1 Pancreatic ductal adenocarcinoma (PDAC) is the fourth-leading cause of cancer-related mortality in the United States having the worst prognosis with 5-year survival rate of 10%. In this project, we pursue the development of a sequential therapy using targeted stimuli-responsive drug delivery nanocarriers for the treatment of advanced PDAC. https://features.charlotte.edu/juan-vivero-escoto